Anti-PPBP/CXCL7/NAP-2 antibody [SAA0464] (STJA0027641)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2ak
General Information
| Short Description | Mouse monoclonal Platelet Basic Protein antibody for use in ELISA and FC in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/FC |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA0464 |
| Isotype | IgG2ak |
| Conjugation | Unconjugated |
| Concentration | 1 mg/ml |
| Purification | Protein A/G purified from cell culture supernatant. |
| Formulation | 0.01M PBS, pH 7.4, 0.09% Sodium azide. |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
Target Information
| Gene Symbol | PPBP |
| Gene ID | 5473 |
| Uniprot ID | CXCL7_HUMAN |
Additional Info
| Function | LA-PF4 stimulates DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by human synovial cells. NAP-2 is a ligand for CXCR1 and CXCR2, and NAP-2, NAP-2(73), NAP-2(74), NAP-2(1-66), and most potent NAP-2(1-63) are chemoattractants and activators for neutrophils. TC-1 and TC-2 are antibacterial proteins, in vitro released from activated platelet alpha-granules. CTAP-III(1-81) is more potent than CTAP-III desensitize chemokine-induced neutrophil activation. |
| Protein Name | Platelet Basic ProteinPbpC-X-C Motif Chemokine 7Leukocyte-Derived Growth FactorLdgfMacrophage-Derived Growth FactorMdgfSmall-Inducible Cytokine B7 Cleaved Into - Connective Tissue-Activating Peptide IiiCtap-IiiLa-Pf4Low-Affinity Platelet Factor Iv - Tc-2 - Connective Tissue-Activating Peptide Iii(1-81Ctap-Iii(1-81 - Beta-ThromboglobulinBeta-Tg - Neutrophil-Activating Peptide 2(74Nap-2(74 - Neutrophil-Activating Peptide 2(73Nap-2(73 - Neutrophil-Activating Peptide 2Nap-2 - Tc-1 - Neutrophil-Activating Peptide 2(1-66Nap-2(1-66 - Neutrophil-Activating Peptide 2(1-63Nap-2(1-63 |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-380108Reactome: R-HSA-418594Reactome: R-HSA-6798695 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Platelet Basic Protein antibodyAnti-Pbp antibodyAnti-C-X-C Motif Chemokine 7 antibodyAnti-Leukocyte-Derived Growth Factor antibodyAnti-Ldgf antibodyAnti-Macrophage-Derived Growth Factor antibodyAnti-Mdgf antibodyAnti-Small-Inducible Cytokine B7 Cleaved Into - Connective Tissue-Activating Peptide Iii antibodyAnti-Ctap-Iii antibodyAnti-La-Pf4 antibodyAnti-Low-Affinity Platelet Factor Iv - Tc-2 - Connective Tissue-Activating Peptide Iii(1-81 antibodyAnti-Ctap-Iii(1-81 - Beta-Thromboglobulin antibodyAnti-Beta-Tg - Neutrophil-Activating Peptide 2(74 antibodyAnti-Nap-2(74 - Neutrophil-Activating Peptide 2(73 antibodyAnti-Nap-2(73 - Neutrophil-Activating Peptide 2 antibodyAnti-Nap-2 - Tc-1 - Neutrophil-Activating Peptide 2(1-66 antibodyAnti-Nap-2(1-66 - Neutrophil-Activating Peptide 2(1-63 antibodyAnti-Nap-2(1-63 antibodyAnti-PPBP antibodyAnti-CTAP3 antibodyAnti-CXCL7 antibodyAnti-SCYB7 antibodyAnti-TGB1 antibodyAnti-THBGB1 antibody |
Information sourced from Uniprot.org