Host: |
Mouse |
Applications: |
IF/IHC |
Reactivity: |
Human/Rat/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Mouse monoclonal antibody anti-Peroxisome proliferator-activated receptor delta is suitable for use in Immunofluorescence and Immunohistochemistry research applications. |
Clonality: |
Monoclonal |
Clone ID: |
2F9 |
Conjugation: |
Unconjugated |
Isotype: |
IgG1 |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
IF 1:50-200IHC 1:100-200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
PPARD |
Gene ID: |
5467 |
Uniprot ID: |
PPARD_HUMAN |
Specificity: |
PPAR Delta protein detects endogenous levels of PPAR Delta |
Immunogen: |
Recombinant Protein of PPAR Delta of PPAR Delta |
Post Translational Modifications | 'Lys-48'-linked polyubiquitinated.leading to proteasomal degradation. Deubiquitinated and stabilized by OTUD3. |
Function | Ligand-activated transcription factor key mediator of energy metabolism in adipose tissues. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter elements of target genes. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the acyl-CoA oxidase gene. Decreases expression of NPC1L1 once activated by a ligand. |
Protein Name | Peroxisome Proliferator-Activated Receptor DeltaPpar-DeltaNuciNuclear Hormone Receptor 1Nuc1Nuclear Receptor Subfamily 1 Group C Member 2Peroxisome Proliferator-Activated Receptor BetaPpar-Beta |
Database Links | Reactome: R-HSA-200425Reactome: R-HSA-204174Reactome: R-HSA-383280Reactome: R-HSA-5362517 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Peroxisome Proliferator-Activated Receptor Delta antibodyAnti-Ppar-Delta antibodyAnti-Nuci antibodyAnti-Nuclear Hormone Receptor 1 antibodyAnti-Nuc1 antibodyAnti-Nuclear Receptor Subfamily 1 Group C Member 2 antibodyAnti-Peroxisome Proliferator-Activated Receptor Beta antibodyAnti-Ppar-Beta antibodyAnti-PPARD antibodyAnti-NR1C2 antibodyAnti-PPARB antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance