| Host: | Rabbit |
| Applications: | ELISA/IHC/IP/WB |
| Reactivity: | Human/Monkey/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-PP2A-alpha (410-486) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Purification: | Affinity Purified |
| Concentration: | 0.5-1.5 µg/µl |
| Dilution Range: | WB: 1:500-1:5, 000 ELISA: 1:50, 000 IP: 1:200 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | PPP2R5A |
| Gene ID: | 5525 |
| Uniprot ID: | 2A5A_HUMAN |
| Immunogen Region: | 410-486 |
| Immunogen: | Synthetic peptide taken within amino acid region 410-486 on human Serine/Threonine-Protein Phosphatase 2A, B56-Alpha subunit. |
| Tissue Specificity | Widely expressed with the highest expression in heart and skeletal muscle. |
| Post Translational Modifications | Phosphorylated on serine residues. |
| Function | The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. |
| Protein Name | Serine/Threonine-Protein Phosphatase 2a 56 Kda Regulatory Subunit Alpha Isoform Pp2a B Subunit Isoform B'-Alpha Pp2a B Subunit Isoform B56-Alpha Pp2a B Subunit Isoform Pr61-Alpha Pr61alpha Pp2a B Subunit Isoform R5-Alpha |
| Database Links | Reactome: R-HSA-141444 Reactome: R-HSA-195253 Reactome: R-HSA-196299 Reactome: R-HSA-2467813 Reactome: R-HSA-2500257 Reactome: R-HSA-389513 Reactome: R-HSA-432142 Reactome: R-HSA-4641262 Reactome: R-HSA-5339716 Reactome: R-HSA-5358747 Reactome: R-HSA-5358749 Reactome: R-HSA-5358751 Reactome: R-HSA-5358752 Reactome: R-HSA-5467337 Reactome: R-HSA-5467340 Reactome: R-HSA-5467348 Reactome: R-HSA-5663220 Reactome: R-HSA-5673000 Reactome: R-HSA-5675221 Reactome: R-HSA-6811558 Reactome: R-HSA-68877 Reactome: R-HSA-9648025 Reactome: R-HSA-9833482 |
| Cellular Localisation | Cytoplasm Nucleus Chromosome Centromere From Mitotic Prophase To Metaphase Localizes At The Inner Centromere Between A Pair Of Sister Kinetochores Decreased Expression At The Onset Of Anaphase |
| Alternative Antibody Names | Anti-Serine/Threonine-Protein Phosphatase 2a 56 Kda Regulatory Subunit Alpha Isoform antibody Anti-Pp2a B Subunit Isoform B'-Alpha antibody Anti-Pp2a B Subunit Isoform B56-Alpha antibody Anti-Pp2a B Subunit Isoform Pr61-Alpha antibody Anti-Pr61alpha antibody Anti-Pp2a B Subunit Isoform R5-Alpha antibody Anti-PPP2R5A antibody |
Information sourced from Uniprot.org