| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-POU domain, class 4, transcription factor 3 (231-280 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000ELISA 1:5000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | POU4F3 |
| Gene ID: | 5459 |
| Uniprot ID: | PO4F3_HUMAN |
| Immunogen Region: | 231-280 aa |
| Specificity: | Brn-3 Polyclonal Antibody detects endogenous levels of Brn-3 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human POU4F3 at the amino acid range 231-280 |
| Function | Acts as a transcriptional activator. Acts by binding to sequences related to the consensus octamer motif 5'-ATGCAAAT-3' in the regulatory regions of its target genes. Involved in the auditory system development, required for terminal differentiation of hair cells in the inner ear. |
| Protein Name | Pou Domain - Class 4 - Transcription Factor 3Brain-Specific Homeobox/Pou Domain Protein 3cBrain-3cBrn-3c |
| Database Links | |
| Cellular Localisation | NucleusCytoplasmPreferentially Localized In The Nucleus |
| Alternative Antibody Names | Anti-Pou Domain - Class 4 - Transcription Factor 3 antibodyAnti-Brain-Specific Homeobox/Pou Domain Protein 3c antibodyAnti-Brain-3c antibodyAnti-Brn-3c antibodyAnti-POU4F3 antibodyAnti-BRN3C antibody |
Information sourced from Uniprot.org
