Anti-POU3F3/BRN1/OCT8 antibody (Internal) (STJ72235)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-POU3F3/BRN1/OCT8 (Internal) is suitable for use in ELISA, Western Blot, Immunofluorescence and Flow Cytometry research applications. |
| Applications | Pep-ELISA/WB/IF/FC |
| Host | Goat |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:4000.WB: Approx 48kDa band observed in Mouse Spinal Cord lysates and approx. 50kDa in Mouse Brain lysates (calculated MW of 50.3kDa according to Human NP_006227.1 and 50.2kDa according to Mouse |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | POU3F3 |
| Gene ID | 5455 |
| Uniprot ID | PO3F3_HUMAN |
| Accession Number | NP_006227.1 |
| Immunogen Region | Internal |
| Immunogen Sequence | HMLSHAHQWVTAL |
Additional Info
| Function | Transcription factor that acts synergistically with SOX11 and SOX4. Plays a role in neuronal development. Is implicated in an enhancer activity at the embryonic met-mesencephalic junction.the enhancer element contains the octamer motif (5'-ATTTGCAT-3'). |
| Protein Name | Pou Domain - Class 3 - Transcription Factor 3Brain-Specific Homeobox/Pou Domain Protein 1Brain-1Brn-1Octamer-Binding Protein 8Oct-8Octamer-Binding Transcription Factor 8Otf-8 |
| Database Links | Reactome: R-HSA-9831926 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Pou Domain - Class 3 - Transcription Factor 3 antibodyAnti-Brain-Specific Homeobox/Pou Domain Protein 1 antibodyAnti-Brain-1 antibodyAnti-Brn-1 antibodyAnti-Octamer-Binding Protein 8 antibodyAnti-Oct-8 antibodyAnti-Octamer-Binding Transcription Factor 8 antibodyAnti-Otf-8 antibodyAnti-POU3F3 antibodyAnti-BRN1 antibodyAnti-OTF8 antibody |
Information sourced from Uniprot.org