| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-POU domain, class 3, transcription factor 1 (311-360) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000ELISA 1:20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | POU3F1 |
| Gene ID: | 5453 |
| Uniprot ID: | PO3F1_HUMAN |
| Immunogen Region: | 311-360 |
| Specificity: | Oct-6 Polyclonal Antibody detects endogenous levels of 40822 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human OCT6. AA range:311-360 |
| Tissue Specificity | Expressed in embryonal stem cells and in the developing brain. |
| Function | Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Acts as a transcriptional activator when binding cooperatively with SOX4, SOX11, or SOX12 to gene promoters. Acts as a transcriptional repressor of myelin-specific genes. |
| Protein Name | Pou Domain - Class 3 - Transcription Factor 1Octamer-Binding Protein 6Oct-6Octamer-Binding Transcription Factor 6Otf-6Pou Domain Transcription Factor Scip |
| Database Links | Reactome: R-HSA-9619665Reactome: R-HSA-9823739Reactome: R-HSA-9832991 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Pou Domain - Class 3 - Transcription Factor 1 antibodyAnti-Octamer-Binding Protein 6 antibodyAnti-Oct-6 antibodyAnti-Octamer-Binding Transcription Factor 6 antibodyAnti-Otf-6 antibodyAnti-Pou Domain Transcription Factor Scip antibodyAnti-POU3F1 antibodyAnti-OCT6 antibodyAnti-OTF6 antibody |
Information sourced from Uniprot.org