| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | POU3F1 |
| Gene ID: | 5453 |
| Uniprot ID: | PO3F1_HUMAN |
| Immunogen Region: | 1-260 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human POU3F1 (NP_002690.3). |
| Immunogen Sequence: | MATTAQYLPRGPGGGAGGTG PLMHPDAAAAAAAAAAAERL HAGAAYREVQKLMHHEWLGA GAGHPVGLAHPQWLPTGGGG GGDWAGGPHLEHGKAGGGGT GRADDGGGGGGFHARLVHQG AAHAGAAWAQGSTAHHLGPA MSPSPGASGGHQPQPLGLYA QAAYPGGGGGGLAGMLAAGG GGAGPGLHHALHEDGHEAQL EPSPPPHLGAHGHAHGHAHA GGLHAAAAHLHPGAGGGGS |
| Tissue Specificity | Expressed in embryonal stem cells and in the developing brain. |
| Function | Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Acts as a transcriptional activator when binding cooperatively with SOX4, SOX11, or SOX12 to gene promoters. Acts as a transcriptional repressor of myelin-specific genes. |
| Protein Name | Pou Domain - Class 3 - Transcription Factor 1Octamer-Binding Protein 6Oct-6Octamer-Binding Transcription Factor 6Otf-6Pou Domain Transcription Factor Scip |
| Database Links | Reactome: R-HSA-9619665Reactome: R-HSA-9823739Reactome: R-HSA-9832991 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Pou Domain - Class 3 - Transcription Factor 1 antibodyAnti-Octamer-Binding Protein 6 antibodyAnti-Oct-6 antibodyAnti-Octamer-Binding Transcription Factor 6 antibodyAnti-Otf-6 antibodyAnti-Pou Domain Transcription Factor Scip antibodyAnti-POU3F1 antibodyAnti-OCT6 antibodyAnti-OTF6 antibody |
Information sourced from Uniprot.org