| Short Description : | Rabbit polyclonal anti-Periostin (C-Term) for use in WB and IHC in Chicken, Human, Mouse, Rat, Bovine, Canine, Feline, Finch, Goat, Guinea Pig, Hamster, Horse, Non-Human Primates, Rabbit, Sheep and Vole samples. Datasheet included with dilution recom |
| Applications: | WB/IHC |
| Host: | Rabbit |
| Reactivity: | Chicken/Human/Mouse/Rat/Bovine/Canine/Feline/Finch/Goat/Guinea Pig/Hamster/Horse/Non-Human Primates/Rabbit/Sheep/Vole |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Purification: | This antibody was antigen affinity purified from serum. |
| Dilution Range: | WB 1:1000IHC 1:100 |
| Formulation: | 100 ul in PBS |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | Postn |
| Gene ID: | 50706 |
| Uniprot ID: | POSTN_MOUSE |
| Immunogen: | Bacterial fusion protein equivalent to a 188-amino acid polypeptide from the C-terminal region of mouse periostin which was comprised of six small alternatively-spliced exons. |
| Immunogen Region: | C-Term |
| Tissue Specificity | Preferentially expressed in periosteum and periodontal ligament. Also expressed in the developing and adult heart. |
| Post Translational Modifications | Gamma-carboxylation is controversial. Gamma-carboxyglutamated.gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation.these residues may be required for binding to calcium. According to a more recent report in human, does not contain vitamin K-dependent gamma-carboxyglutamate residues. |
| Function | Induces cell attachment and spreading and plays a role in cell adhesion. Enhances incorporation of BMP1 in the fibronectin matrix of connective tissues, and subsequent proteolytic activation of lysyl oxidase LOX. |
| Protein Name | PeriostinPnOsteoblast-Specific Factor 2Osf-2 |
| Database Links | |
| Cellular Localisation | Golgi ApparatusSecretedExtracellular SpaceExtracellular MatrixColocalizes With Bmp1 In The Golgi |
| Alternative Antibody Names | Anti-Periostin antibodyAnti-Pn antibodyAnti-Osteoblast-Specific Factor 2 antibodyAnti-Osf-2 antibodyAnti-Postn antibodyAnti-Osf2 antibody |
Information sourced from Uniprot.org
