Western blot of rat lung lysate showing specific immunolabeling of the ~93 kDa periostin protein doublet.

Anti-POSTN antibody (C-Term) (STJA0003745)

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STJA0003745-100
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Host: Rabbit
Applications: WB/IHC
Reactivity: Chicken/Human/Mouse/Rat/Bovine/Canine/Feline/Finch/Goat/Guinea Pig/Hamster/Horse/Non-Human Primates/Rabbit/Sheep/Vole
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Periostin (C-Term) is suitable for use in Western Blot and Immunohistochemistry research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 100 ul in PBS
Purification: This antibody was antigen affinity purified from serum.
Dilution Range: WB 1:1000
IHC 1:100
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: Postn
Gene ID: 50706
Uniprot ID: POSTN_MOUSE
Immunogen Region: C-Term
Immunogen: Bacterial fusion protein equivalent to a 188-amino acid polypeptide from the C-terminal region of mouse periostin which was comprised of six small alternatively-spliced exons.
Tissue Specificity Preferentially expressed in periosteum and periodontal ligament. Also expressed in the developing and adult heart.
Post Translational Modifications Gamma-carboxylation is controversial. Gamma-carboxyglutamated.gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation.these residues may be required for binding to calcium. According to a more recent report in human, does not contain vitamin K-dependent gamma-carboxyglutamate residues.
Function Induces cell attachment and spreading and plays a role in cell adhesion. Enhances incorporation of BMP1 in the fibronectin matrix of connective tissues, and subsequent proteolytic activation of lysyl oxidase LOX.
Protein Name Periostin
Pn
Osteoblast-Specific Factor 2
Osf-2
Cellular Localisation Golgi Apparatus
Secreted
Extracellular Space
Extracellular Matrix
Colocalizes With Bmp1 In The Golgi
Alternative Antibody Names Anti-Periostin antibody
Anti-Pn antibody
Anti-Osteoblast-Specific Factor 2 antibody
Anti-Osf-2 antibody
Anti-Postn antibody
Anti-Osf2 antibody

Information sourced from Uniprot.org

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