Anti-PON2 antibody [R05-1J3] (STJA0034743)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant protein of human PON2
General Information
| Short Description | Rabbit monoclonal anti-PON2 for use in WB, IHC-P and IP in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IP |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R05-1J3 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100IP 1:20 |
| Formulation | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | PON2 |
| Gene ID | 5445 |
| Uniprot ID | PON2_HUMAN |
| Immunogen | Recombinant protein of human PON2 |
Additional Info
| Tissue Specificity | Widely expressed with highest expression in liver, lung, placenta, testis and heart. |
| Post Translational Modifications | The signal sequence is not cleaved. |
| Function | Capable of hydrolyzing lactones and a number of aromatic carboxylic acid esters. Has antioxidant activity. Is not associated with high density lipoprotein. Prevents LDL lipid peroxidation, reverses the oxidation of mildly oxidized LDL, and inhibits the ability of MM-LDL to induce monocyte chemotaxis. |
| Protein Name | Serum Paraoxonase/Arylesterase 2Pon 2Aromatic Esterase 2A-Esterase 2Serum Aryldialkylphosphatase 2 |
| Database Links | Reactome: R-HSA-2142688 |
| Cellular Localisation | MembranePeripheral Membrane Protein |
| Alternative Antibody Names | Anti-Serum Paraoxonase/Arylesterase 2 antibodyAnti-Pon 2 antibodyAnti-Aromatic Esterase 2 antibodyAnti-A-Esterase 2 antibodyAnti-Serum Aryldialkylphosphatase 2 antibodyAnti-PON2 antibody |
Information sourced from Uniprot.org