| Short Description : | Rabbit polyclonal POMP (1-141) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | POMP |
| Gene ID: | 51371 |
| Uniprot ID: | POMP_HUMAN |
| Immunogen Region: | 1-141 |
| Immunogen Sequence: | MNARGLGSELKDSIPVTELS ASGPFESHDLLRKGFSCVKN ELLPSHPLELSEKNFQLNQD KMNFSTLRNIQGLFAPLKLQ MEFKAVQQVQRLPFLSSSNL SLDVLRGNDETIGFEDILND PSQSEVMGEPHLMVEYKLGL L |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-141 of human POMP (NP_057016.1). |
| Tissue Specificity | Strongly expressed from the basal layer to the granular layer of healthy epidermis, whereas in KLICK patients there is a gradual decrease of expression toward the granular layer. |
| Function | Molecular chaperone essential for the assembly of standard proteasomes and immunoproteasomes. Degraded after completion of proteasome maturation. Mediates the association of 20S preproteasome with the endoplasmic reticulum. |
| Protein Name | Proteasome Maturation ProteinProteassemblinProtein Ump1 HomologHump1Voltage-Gated K Channel Beta Subunit 4.1 |
| Database Links | Reactome: R-HSA-9907900 |
| Cellular Localisation | CytoplasmCytosolNucleusMicrosome Membrane |
| Alternative Antibody Names | Anti-Proteasome Maturation Protein antibodyAnti-Proteassemblin antibodyAnti-Protein Ump1 Homolog antibodyAnti-Hump1 antibodyAnti-Voltage-Gated K Channel Beta Subunit 4.1 antibodyAnti-POMP antibodyAnti-C13orf12 antibodyAnti-UMP1 antibodyAnti-HSPC014 antibodyAnti-HSPC036 antibodyAnti-PNAS-110 antibody |
Information sourced from Uniprot.org
