Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-POLR1C (1-200) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
POLR1C |
Gene ID: |
9533 |
Uniprot ID: |
RPAC1_HUMAN |
Immunogen Region: |
1-200 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human POLR1C (NP_976035.1). |
Immunogen Sequence: |
MAASQAVEEMRSRVVLGEFG VRNVHTTDFPGNYSGYDDAW DQDRFEKNFRVDVVHMDENS LEFDMVGIDAAIANAFRRIL LAEVPTMAVEKVLVYNNTSI VQDEILAHRLGLIPIHADPR LFEYRNQGDEEGTEIDTLQF RLQVRCTRNPHAAKDSSDPN ELYVNHKVYTRHMTWIPLGN QADLFPEGTIRPVHDDILIA |
Function | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively. RPAC1 is part of the Pol core element with the central large cleft and probably a clamp element that moves to open and close the cleft. |
Protein Name | Dna-Directed Rna Polymerases I And Iii Subunit Rpac1Dna-Directed Rna Polymerase I Subunit CRna Polymerases I And Iii Subunit Ac1Ac40Dna-Directed Rna Polymerases I And Iii 40 Kda PolypeptideRpa40Rpa39Rpc40 |
Database Links | Reactome: R-HSA-1834949Reactome: R-HSA-427413Reactome: R-HSA-5250924Reactome: R-HSA-73762Reactome: R-HSA-73772Reactome: R-HSA-73780Reactome: R-HSA-73863Reactome: R-HSA-73980Reactome: R-HSA-749476Reactome: R-HSA-76061Reactome: R-HSA-76066Reactome: R-HSA-76071 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Dna-Directed Rna Polymerases I And Iii Subunit Rpac1 antibodyAnti-Dna-Directed Rna Polymerase I Subunit C antibodyAnti-Rna Polymerases I And Iii Subunit Ac1 antibodyAnti-Ac40 antibodyAnti-Dna-Directed Rna Polymerases I And Iii 40 Kda Polypeptide antibodyAnti-Rpa40 antibodyAnti-Rpa39 antibodyAnti-Rpc40 antibodyAnti-POLR1C antibodyAnti-POLR1E antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance