| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | POLR1C |
| Gene ID: | 9533 |
| Uniprot ID: | RPAC1_HUMAN |
| Immunogen Region: | 1-200 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human POLR1C (NP_976035.1). |
| Immunogen Sequence: | MAASQAVEEMRSRVVLGEFG VRNVHTTDFPGNYSGYDDAW DQDRFEKNFRVDVVHMDENS LEFDMVGIDAAIANAFRRIL LAEVPTMAVEKVLVYNNTSI VQDEILAHRLGLIPIHADPR LFEYRNQGDEEGTEIDTLQF RLQVRCTRNPHAAKDSSDPN ELYVNHKVYTRHMTWIPLGN QADLFPEGTIRPVHDDILIA |
| Function | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I and III which synthesize ribosomal RNA precursors and short non-coding RNAs including 5S rRNA, snRNAs, tRNAs and miRNAs, respectively. POLR1C/RPAC1 is part of the polymerase core and may function as a clamp element that moves to open and close the cleft. |
| Protein Name | Dna-Directed Rna Polymerases I And Iii Subunit Rpac1Dna-Directed Rna Polymerase I Subunit CRna Polymerases I And Iii Subunit Ac1Ac40Dna-Directed Rna Polymerases I And Iii 40 Kda PolypeptideRpa40Rpa39Rpc40 |
| Database Links | Reactome: R-HSA-1834949Reactome: R-HSA-427413Reactome: R-HSA-5250924Reactome: R-HSA-73762Reactome: R-HSA-73772Reactome: R-HSA-73780Reactome: R-HSA-73863Reactome: R-HSA-73980Reactome: R-HSA-749476Reactome: R-HSA-76061Reactome: R-HSA-76066Reactome: R-HSA-76071 |
| Cellular Localisation | NucleusNucleolusCytoplasmCytosol |
| Alternative Antibody Names | Anti-Dna-Directed Rna Polymerases I And Iii Subunit Rpac1 antibodyAnti-Dna-Directed Rna Polymerase I Subunit C antibodyAnti-Rna Polymerases I And Iii Subunit Ac1 antibodyAnti-Ac40 antibodyAnti-Dna-Directed Rna Polymerases I And Iii 40 Kda Polypeptide antibodyAnti-Rpa40 antibodyAnti-Rpa39 antibodyAnti-Rpc40 antibodyAnti-POLR1C antibodyAnti-POLR1E antibody |
Information sourced from Uniprot.org
