Function | Plays a role in mitotic cell cycle progression and is involved in kinetochore assembly and mitotic sister chromatid cohesion. Probably through its association with CBX5 plays a role in mitotic chromosome segregation by regulating aurora kinase B/AURKB activation and AURKB and CBX5 dissociation from chromosome arms. Promotes the repair of DNA double-strand breaks through the homologous recombination pathway. |
Protein Name | Pogo Transposable Element With Znf DomainSuppressor Of Hairy Wing Homolog 5Zinc Finger Protein 280eZinc Finger Protein 635 |
Cellular Localisation | NucleusChromosomeCytoplasmAccording To Some AuthorsIt Is Not Localized To Mitotic ChromatinRecruited To Trimethylated 'Lys-9' Of Histone H3 (H3k9me3) |
Alternative Antibody Names | Anti-Pogo Transposable Element With Znf Domain antibodyAnti-Suppressor Of Hairy Wing Homolog 5 antibodyAnti-Zinc Finger Protein 280e antibodyAnti-Zinc Finger Protein 635 antibodyAnti-POGZ antibodyAnti-KIAA0461 antibodyAnti-SUHW5 antibodyAnti-ZNF280E antibodyAnti-ZNF635 antibodyAnti-Nbla00003 antibody |
Information sourced from Uniprot.org