Anti-POGLUT1 antibody (STJA0009181)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human KTELC1
General Information
| Short Description | Rabbit polyclonal anti-Protein O-glucosyltransferase 1 for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | POGLUT1 |
| Gene ID | 56983 |
| Uniprot ID | PGLT1_HUMAN |
| Immunogen | Synthesized peptide derived from human KTELC1 |
| Specificity | This antibody detects endogenous levels of KTELC1 at Human, Mouse |
Additional Info
| Function | Dual specificity glycosyltransferase that catalyzes the transfer of glucose and xylose from UDP-glucose and UDP-xylose, respectively, to a serine residue found in the consensus sequence of C-X-S-X-P-C. Specifically targets extracellular EGF repeats of protein such as CRB2, F7, F9 and NOTCH2. Acts as a positive regulator of Notch signaling by mediating O-glucosylation of Notch, leading to regulate muscle development. Notch glucosylation does not affect Notch ligand binding. Required during early development to promote gastrulation: acts by mediating O-glucosylation of CRB2, which is required for CRB2 localization to the cell membrane. |
| Protein Name | Protein O-Glucosyltransferase 1Cap10-Like 46 Kda ProteinHclp46Ktel Motif-Containing Protein 1Myelodysplastic Syndromes Relative ProteinO-Glucosyltransferase Rumi HomologHrumiProtein O-Xylosyltransferase Poglut1 |
| Database Links | Reactome: R-HSA-1912399 |
| Cellular Localisation | Endoplasmic Reticulum Lumen |
| Alternative Antibody Names | Anti-Protein O-Glucosyltransferase 1 antibodyAnti-Cap10-Like 46 Kda Protein antibodyAnti-Hclp46 antibodyAnti-Ktel Motif-Containing Protein 1 antibodyAnti-Myelodysplastic Syndromes Relative Protein antibodyAnti-O-Glucosyltransferase Rumi Homolog antibodyAnti-Hrumi antibodyAnti-Protein O-Xylosyltransferase Poglut1 antibodyAnti-POGLUT1 antibodyAnti-C3orf9 antibodyAnti-CLP46 antibodyAnti-KTELC1 antibodyAnti-MDSRP antibodyAnti-MDS010 antibodyAnti-UNQ490 antibodyAnti-PRO1006 antibody |
Information sourced from Uniprot.org