| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | PMP22 |
| Gene ID: | 5376 |
| Uniprot ID: | PMP22_HUMAN |
| Immunogen Region: | 50-150 aa |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human PMP22 (NP_000295.1). |
| Immunogen Sequence: | VHHCFSSSPNEWLQSVQATM ILSIIFSILSLFLFFCQLFT LTKGGRFYITGIFQILAGLC VMSAAAIYTVRHPEWHLNSD YSYGFAYILAWVAFPLALLS G |
| Post Translational Modifications | Ubiquitinated by the DCX(DCAF13) E3 ubiquitin ligase complex, leading to its degradation. |
| Function | Might be involved in growth regulation, and in myelinization in the peripheral nervous system. |
| Protein Name | Peripheral Myelin Protein 22Pmp-22Growth Arrest-Specific Protein 3Gas-3 |
| Database Links | Reactome: R-HSA-9619665 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Peripheral Myelin Protein 22 antibodyAnti-Pmp-22 antibodyAnti-Growth Arrest-Specific Protein 3 antibodyAnti-Gas-3 antibodyAnti-PMP22 antibodyAnti-GAS3 antibody |
Information sourced from Uniprot.org