Anti-PMF 1 antibody [R07-1G3] (STJA0035326)

SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant protein of human PMF-1
STJA0035326
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General Information

Short DescriptionRabbit monoclonal anti-PMF 1 for use in WB and IP in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/IP
HostRabbit
ReactivityHuman/Mouse/Rat
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDR07-1G3
IsotypeIgG
ConjugationUnconjugated
Concentration0.3 mg/mL
PurificationAffinity Purified
Dilution RangeWB 1:500-1:1000
IP 1:20
Formulation50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Storage InstructionStore at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.

Target Information

Gene SymbolPMF1
Gene ID100527963/11243
Uniprot IDPMF1_HUMAN
ImmunogenRecombinant protein of human PMF-1

Additional Info

Tissue Specificity Highest levels of expression in heart and skeletal muscle, with significant levels expressed in kidney and liver.
Function Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis. May act as a cotranscription partner of NFE2L2 involved in regulation of polyamine-induced transcription of SSAT.
Protein Name Polyamine-Modulated Factor 1
Pmf-1
Database Links Reactome: R-HSA-141444
Reactome: R-HSA-2467813
Reactome: R-HSA-2500257
Reactome: R-HSA-5663220
Reactome: R-HSA-68877
Reactome: R-HSA-9648025
Cellular Localisation Nucleus
Chromosome
Centromere
Kinetochore
Associated With The Kinetochore
Alternative Antibody Names Anti-Polyamine-Modulated Factor 1 antibody
Anti-Pmf-1 antibody
Anti-PMF1 antibody

Information sourced from Uniprot.org

Citations

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