Anti-PLXND1 antibody (C-Term) (STJA0005544)

SKU:
STJA0005544-100

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Plexin D1 (C-Term) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS + 1 mg/ml BSA, 0.05% NaN3 and 50% glycerol
Purification: Antigen Affinity Purified
Dilution Range: WB 1:500
IHC
ICC
IP
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PLXND1
Gene ID: 23129
Uniprot ID: PLXD1_HUMAN
Immunogen Region: C-Term
Specificity: The antibody detects 215 and 195 kDa bands corresponding to the apparent molecular mass of Plexin D1 variants in human umbilical vein endothelial cells.
Immunogen: Plexin D1 synthetic peptide (coupled to carrier protein) corresponding to amino acids from the C-terminal region of human Plexin D1. This sequence is well conserved in rat and mouse Plexin D1, and has some homology to other Plexin family members.
Function Cell surface receptor for SEMA4A and for class 3 semaphorins, such as SEMA3A, SEMA3C and SEMA3E. Plays an important role in cell-cell signaling, and in regulating the migration of a wide spectrum of cell types. Regulates the migration of thymocytes in the medulla. Regulates endothelial cell migration. Plays an important role in ensuring the specificity of synapse formation. Required for normal development of the heart and vasculature. Mediates anti-angiogenic signaling in response to SEMA3E.
Protein Name Plexin-D1
Database Links Reactome: R-HSA-416700
Reactome: R-HSA-9013508
Reactome: R-HSA-9696270
Cellular Localisation Cell Membrane
Single-Pass Membrane Protein
Cell Projection
Lamellipodium Membrane
Alternative Antibody Names Anti-Plexin-D1 antibody
Anti-PLXND1 antibody
Anti-KIAA0620 antibody

Information sourced from Uniprot.org

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