Anti-PLXNB1 antibody [SAA1502] (STJA0019930)

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STJA0019930
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Covered by St John's Laboratory Guarantee

Host: Mouse
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS
Short Description : Mouse monoclonal antibody anti-Plexin-B1 is suitable for use in ELISA research applications.
Clonality : Monoclonal
Clone ID : SAA1502
Conjugation: Unconjugated
Isotype: IgG2a
Formulation: 0.01M PBS
Purification: Protein A/G purified from cell culture supernatant
Concentration: 1 mg/mL
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months
Gene Symbol: PLXNB1
Gene ID: 5364
Uniprot ID: PLXB1_HUMAN
Post Translational Modifications Phosphorylated on tyrosine residues by ERBB2 and MET upon SEMA4D binding. Proteolytic processing favors heterodimerization with PLXNB2 and SEMA4D binding.
Function Receptor for SEMA4D. Plays a role in GABAergic synapse development. Mediates SEMA4A- and SEMA4D-dependent inhibitory synapse development. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.
Protein Name Plexin-B1
Semaphorin Receptor Sep
Database Links Reactome: R-HSA-416482
Reactome: R-HSA-416550
Reactome: R-HSA-416572
Reactome: R-HSA-9013405
Cellular Localisation Isoform 1: Cell Membrane
Single-Pass Type I Membrane Protein
Isoform 2: Secreted
Isoform 3: Secreted
Alternative Antibody Names Anti-Plexin-B1 antibody
Anti-Semaphorin Receptor Sep antibody
Anti-PLXNB1 antibody
Anti-KIAA0407 antibody
Anti-PLXN5 antibody
Anti-SEP antibody

Information sourced from Uniprot.org

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