| Function | Catalyzes metal ion-induced ATP-independent rapid bidirectional and non-specific movement of phospholipids (lipid scrambling or lipid flip-flop) between the inner and outer leaflet of the plasma membrane and participates in the redistribution of phospholipids between membrane leaflets. Metal ions bind to the calcium-binding site and induce conformation change in the protein. Has a greater affi nity for Ca(2+) than Mg(2+) and Zn(2+). |
| Protein Name | Phospholipid Scramblase 4Pl Scramblase 4Ca(2+-Dependent Phospholipid Scramblase 4Cell Growth-Inhibiting Gene 43 ProteinTra1 |
| Database Links | |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane ProteinLipid-AnchorCytoplasmic SideNucleusPalmitoylation Regulates Its Localization To The Cell Membrane Or The NucleusTrafficking To The Cell Membrane Is Dependent Upon Palmitoylation Whereas In The Absence Of PalmitoylationLocalizes To The Nucleus |
| Alternative Antibody Names | Anti-Phospholipid Scramblase 4 antibodyAnti-Pl Scramblase 4 antibodyAnti-Ca(2+-Dependent Phospholipid Scramblase 4 antibodyAnti-Cell Growth-Inhibiting Gene 43 Protein antibodyAnti-Tra1 antibodyAnti-PLSCR4 antibodyAnti-GIG43 antibody |
Information sourced from Uniprot.org
