| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal anti-Perilipin-2 for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PLIN2 |
| Gene ID: | 123 |
| Uniprot ID: | PLIN2_HUMAN |
| Specificity: | PLIN2 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from part of the human protein |
| Post Translational Modifications | Acylated.primarily with C14, C16 and C18 fatty acids. Phosphorylation at Tyr-232 by isoform 1 of CHKA (CHKalpha2) promotes dissociation from lipid droplets: dissociation is followed by recruitment of autophagosome machinery to lipid droplets and subsequent lipid droplet lipolysis. Polyubiquitination of Nt-acetylatable A-PLIN2 by MARCHF6 lead to degradation by 26S proteasomes. |
| Function | Structural component of lipid droplets, which is required for the formation and maintenance of lipid storage droplets. |
| Protein Name | Perilipin-2AdipophilinAdipose Differentiation-Related ProteinAdrp |
| Database Links | Reactome: R-HSA-1989781Reactome: R-HSA-9613354Reactome: R-HSA-9613829Reactome: R-HSA-9615710Reactome: R-HSA-9841922 |
| Cellular Localisation | MembranePeripheral Membrane ProteinLipid Droplet |
| Alternative Antibody Names | Anti-Perilipin-2 antibodyAnti-Adipophilin antibodyAnti-Adipose Differentiation-Related Protein antibodyAnti-Adrp antibodyAnti-PLIN2 antibodyAnti-ADFP antibody |
Information sourced from Uniprot.org
