| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Pleckstrin homology domain-containing family H member 2 (565-615 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:1000-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PLEKHH2 |
| Gene ID: |
130271 |
| Uniprot ID: |
PKHH2_HUMAN |
| Immunogen Region: |
565-615 aa |
| Specificity: |
This antibody detects endogenous levels of human PKHH2 |
| Immunogen: |
Synthesized peptide derived from the human PKHH2 at the amino acid range 565-615 |
| Function | In the kidney glomerulus may play a role in linking podocyte foot processes to the glomerular basement membrane. May be involved in stabilization of F-actin by attenuating its depolymerization. Can recruit TGFB1I1 from focal adhesions to podocyte lamellipodia. |
| Protein Name | Pleckstrin Homology Domain-Containing Family H Member 2 |
| Cellular Localisation | CytoplasmCytoskeletonCell MembranePeripheral Membrane ProteinCytoplasmic SideCell ProjectionLamellipodiumLocalizes To Foot Process Of PodocytesLocalization To Peripheral Regions Of Lamellipodia Seems To Be Dependent On Pi3k |
| Alternative Antibody Names | Anti-Pleckstrin Homology Domain-Containing Family H Member 2 antibodyAnti-PLEKHH2 antibodyAnti-KIAA2028 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
