| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Pleckstrin homology domain-containing family H member 2 (565-615 aa) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:1000-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PLEKHH2 |
| Gene ID: | 130271 |
| Uniprot ID: | PKHH2_HUMAN |
| Immunogen Region: | 565-615 aa |
| Specificity: | This antibody detects endogenous levels of human PKHH2 |
| Immunogen: | Synthesized peptide derived from the human PKHH2 at the amino acid range 565-615 |
| Function | In the kidney glomerulus may play a role in linking podocyte foot processes to the glomerular basement membrane. May be involved in stabilization of F-actin by attenuating its depolymerization. Can recruit TGFB1I1 from focal adhesions to podocyte lamellipodia. |
| Protein Name | Pleckstrin Homology Domain-Containing Family H Member 2 |
| Cellular Localisation | CytoplasmCytoskeletonCell MembranePeripheral Membrane ProteinCytoplasmic SideCell ProjectionLamellipodiumLocalizes To Foot Process Of PodocytesLocalization To Peripheral Regions Of Lamellipodia Seems To Be Dependent On Pi3k |
| Alternative Antibody Names | Anti-Pleckstrin Homology Domain-Containing Family H Member 2 antibodyAnti-PLEKHH2 antibodyAnti-KIAA2028 antibody |
Information sourced from Uniprot.org