Tissue Specificity | Highly expressed in skeletal muscle, thymus, pancreas, placenta and lung. Detected at low levels in brain, heart, peripheral blood leukocytes, testis, ovary, spinal cord, thyroid, kidney, liver, small intestine and colon. |
Function | Binds specifically to phosphatidylinositol 3,4-diphosphate (PtdIns3,4P2), but not to other phosphoinositides. May recruit other proteins to the plasma membrane. |
Protein Name | Pleckstrin Homology Domain-Containing Family A Member 1Ph Domain-Containing Family A Member 1Tandem Ph Domain-Containing Protein 1Tapp-1 |
Database Links | Reactome: R-HSA-1660499 |
Cellular Localisation | CytoplasmCell MembranePeripheral Membrane ProteinNucleusLocates To The Plasma Membrane After Treatments That Stimulate The Production Of Ptdins34p2 |
Alternative Antibody Names | Anti-Pleckstrin Homology Domain-Containing Family A Member 1 antibodyAnti-Ph Domain-Containing Family A Member 1 antibodyAnti-Tandem Ph Domain-Containing Protein 1 antibodyAnti-Tapp-1 antibodyAnti-PLEKHA1 antibodyAnti-TAPP1 antibody |
Information sourced from Uniprot.org