| Host: |
Rabbit |
| Applications: |
IF |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-PLEKHA1 (285-404) is suitable for use in Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
IF 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PLEKHA1 |
| Gene ID: |
59338 |
| Uniprot ID: |
PKHA1_HUMAN |
| Immunogen Region: |
285-404 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 285-404 of human PLEKHA1 (NP_067635.2). |
| Immunogen Sequence: |
SGAIVAQRGPGRSASSEHPP GPSESKHAFRPTNAATATSH STASRSNSLVSTFTMEKRGF YESLAKVKPGNFKVQTVSPR EPASKVTEQALLRPQSKNGP QEKDCDLVDLDDASLPVSDV |
| Tissue Specificity | Highly expressed in skeletal muscle, thymus, pancreas, placenta and lung. Detected at low levels in brain, heart, peripheral blood leukocytes, testis, ovary, spinal cord, thyroid, kidney, liver, small intestine and colon. |
| Function | Binds specifically to phosphatidylinositol 3,4-diphosphate (PtdIns3,4P2), but not to other phosphoinositides. May recruit other proteins to the plasma membrane. |
| Protein Name | Pleckstrin Homology Domain-Containing Family A Member 1Ph Domain-Containing Family A Member 1Tandem Ph Domain-Containing Protein 1Tapp-1 |
| Database Links | Reactome: R-HSA-1660499 |
| Cellular Localisation | CytoplasmCell MembranePeripheral Membrane ProteinNucleusLocates To The Plasma Membrane After Treatments That Stimulate The Production Of Ptdins34p2 |
| Alternative Antibody Names | Anti-Pleckstrin Homology Domain-Containing Family A Member 1 antibodyAnti-Ph Domain-Containing Family A Member 1 antibodyAnti-Tandem Ph Domain-Containing Protein 1 antibodyAnti-Tapp-1 antibodyAnti-PLEKHA1 antibodyAnti-TAPP1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
