| Tissue Specificity | Widely expressed with highest levels in muscle, heart, placenta and spinal cord. |
| Post Translational Modifications | Phosphorylated by CDK1.regulates dissociation from intermediate filaments during mitosis. |
| Function | Interlinks intermediate filaments with microtubules and microfilaments and anchors intermediate filaments to desmosomes or hemidesmosomes. Could also bind muscle proteins such as actin to membrane complexes in muscle. May be involved not only in the filaments network, but also in the regulation of their dynamics. Structural component of muscle. Isoform 9 plays a major role in the maintenance of myofiber integrity. |
| Protein Name | PlectinPcnPltnHemidesmosomal Protein 1Hd1Plectin-1 |
| Database Links | Reactome: R-HSA-2022090Reactome: R-HSA-264870Reactome: R-HSA-446107 |
| Cellular Localisation | CytoplasmCytoskeletonCell JunctionHemidesmosomeCell ProjectionPodosomeLocalized To The Cortex Of Myotube Podosomes |
| Alternative Antibody Names | Anti-Plectin antibodyAnti-Pcn antibodyAnti-Pltn antibodyAnti-Hemidesmosomal Protein 1 antibodyAnti-Hd1 antibodyAnti-Plectin-1 antibodyAnti-PLEC antibodyAnti-PLEC1 antibody |
Information sourced from Uniprot.org
