• Various whole cell lysates were separated by 10% SDS-PAGE, and the membrane was blotted with anti-uPAR (PT2194) antibody. The HRP-conjugated anti- mouse IgG antibody was used to detect the antibody. Lane 1: Hela Lane 2: HepG2 Lane 3: MCF7Predicted band size: 37kDaObserved band size: 37kDa

Anti-PLAUR antibody (100-200) [PT2194] (STJA0006241)

SKU:
STJA0006241

£46.00 - £226.00
Current Stock:
Host: Mouse
Applications: WB/ELISA
Reactivity: Human/Chicken/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Urokinase plasminogen activator surface receptor (100-200) is suitable for use in Western Blot and ELISA research applications.
Clonality: Monoclonal
Clone ID: PT2194
Conjugation: Unconjugated
Isotype: IgG2bk
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PLAUR
Gene ID: 5329
Uniprot ID: UPAR_HUMAN
Immunogen Region: 100-200
Specificity: This antibody detects endogenous levels of uPAR at H, CHLAE;Not M, R
Immunogen: Synthesized peptide derived from human uPAR AA range: 100-200
Tissue Specificity Expressed in neurons of the rolandic area of the brain (at protein level). Expressed in the brain.
Function Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form.
Protein Name Urokinase Plasminogen Activator Surface Receptor
U-Par
Upar
Monocyte Activation Antigen Mo3
Cd Antigen Cd87
Database Links Reactome: R-HSA-162791
Reactome: R-HSA-6798695
Reactome: R-HSA-75205
Cellular Localisation Cell Membrane
Cell Projection
Invadopodium Membrane
Colocalized With Fap (Seprase) Preferentially At The Cell Surface Of Invadopodia Membrane In A Cytoskeleton-
Integrin- And Vitronectin-Dependent Manner
Isoform 1: Cell Membrane
Lipid-Anchor
Gpi-Anchor
Isoform 2: Secreted
Alternative Antibody Names Anti-Urokinase Plasminogen Activator Surface Receptor antibody
Anti-U-Par antibody
Anti-Upar antibody
Anti-Monocyte Activation Antigen Mo3 antibody
Anti-Cd Antigen Cd87 antibody
Anti-PLAUR antibody
Anti-MO3 antibody
Anti-UPAR antibody

Information sourced from Uniprot.org

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