Anti-PKD1L1 antibody (STJ13101575)

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STJ13101575-100
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Host: Rabbit
Applications: IHC/WB
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-PKD1L1 is suitable for use in Immunohistochemistry and Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Lyophilised
Purification: IgG purified
Dilution Range: IHC, WB. A dilution of 1:1000 to 1:2000 is recommended. The optimal dilution should be determined by the end user.
Storage Instruction: Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Gene Symbol: Pkd1l1
Uniprot ID: PK1L1_MOUSE
Specificity: Specific for PK1L1.
Immunogen: A synthetic peptide from mouse PKD1L1 conjugated to blue carrier protein was used as the antigen.
Function Component of a ciliary calcium channel that controls calcium concentration within primary cilia without affecting cytoplasmic calcium concentration. Forms a heterodimer with PKD2L1 in primary cilia and forms a calcium-permeant ciliary channel that regulates sonic hedgehog/SHH signaling and GLI2 transcription. Does not constitute the pore-forming subunit. Also involved in left/right axis specification downstream of nodal flow: forms a complex with PKD2 in cilia to facilitate flow detection in left/right patterning.
Protein Name Polycystin-1-Like Protein 1
Polycystin-1l1
Pc1-Like 1 Protein
Polycystic Kidney Disease Protein 1-Like 1
Protein Rikishi
Cellular Localisation Cell Projection
Cilium Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Polycystin-1-Like Protein 1 antibody
Anti-Polycystin-1l1 antibody
Anti-Pc1-Like 1 Protein antibody
Anti-Polycystic Kidney Disease Protein 1-Like 1 antibody
Anti-Protein Rikishi antibody
Anti-Pkd1l1 antibody
Anti-Rks antibody

Information sourced from Uniprot.org

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