| Host: | Rabbit |
| Applications: | IHC/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-PKD1L1 is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Lyophilised |
| Purification: | IgG purified |
| Dilution Range: | IHC, WB. A dilution of 1:1000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | PKD1L1 |
| Gene ID: | 168507 |
| Uniprot ID: | PK1L1_HUMAN |
| Specificity: | Specific for PK1L1. |
| Immunogen: | A synthetic peptide from human PKD1L1 conjugated to blue carrier protein was used as the antigen. |
| Function | Component of a ciliary calcium channel that controls calcium concentration within primary cilia without affecting cytoplasmic calcium concentration. Forms a heterodimer with PKD2L1 in primary cilia and forms a calcium-permeant ciliary channel that regulates sonic hedgehog/SHH signaling and GLI2 transcription. Does not constitute the pore-forming subunit. Also involved in left/right axis specification downstream of nodal flow: forms a complex with PKD2 in cilia to facilitate flow detection in left/right patterning. |
| Protein Name | Polycystin-1-Like Protein 1Polycystin-1l1Pc1-Like 1 ProteinPolycystic Kidney Disease Protein 1-Like 1 |
| Cellular Localisation | Cell ProjectionCilium MembraneMulti-Pass Membrane ProteinCilium |
| Alternative Antibody Names | Anti-Polycystin-1-Like Protein 1 antibodyAnti-Polycystin-1l1 antibodyAnti-Pc1-Like 1 Protein antibodyAnti-Polycystic Kidney Disease Protein 1-Like 1 antibodyAnti-PKD1L1 antibodyAnti-UNQ5785 antibodyAnti-PRO19563 antibody |
Information sourced from Uniprot.org