| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: |
PJA1 |
| Gene ID: |
64219 |
| Uniprot ID: |
PJA1_HUMAN |
| Immunogen Region: |
1-240 aa |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human PJA1 (NP_660095.1). |
| Immunogen Sequence: |
MGQESSKPVWPNPTGGYQSN TGRRYGRRHAYVSFRPPTSQ RERIASQRKTNSEVPMHRSA PSQTTKRSRSPFSTTRRSWD DSESSGTNLNIDNEDYSRYP PREYRASGSRRGMAYGHIDS YGADDSEEEGAGPVERPPVR GKTGKFKDDKLYDPEKGARS LAGPPPHFSSFSRDVREERD KLDPVPAARCSASRADFLPQ SSVASQSSSEGKLATKGDSS ERERREQNLPARPSRAPVS |
| Tissue Specificity | Expressed in various regions of the brain including the cerebellum, cerebral cortex, medulla, occipital pole, frontal lobe, temporal lobe and putamen. Highest levels in the cerebral cortex. |
| Post Translational Modifications | Substrate for E2-dependent ubiquitination. |
| Function | Has E2-dependent E3 ubiquitin-protein ligase activity. Ubiquitinates MAGED1 antigen leading to its subsequent degradation by proteasome. May be involved in protein sorting. |
| Protein Name | E3 Ubiquitin-Protein Ligase Praja-1Praja1Ring Finger Protein 70Ring-Type E3 Ubiquitin Transferase Praja-1 |
| Database Links | Reactome: R-HSA-983168 |
| Alternative Antibody Names | Anti-E3 Ubiquitin-Protein Ligase Praja-1 antibodyAnti-Praja1 antibodyAnti-Ring Finger Protein 70 antibodyAnti-Ring-Type E3 Ubiquitin Transferase Praja-1 antibodyAnti-PJA1 antibodyAnti-RNF70 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
