Anti-PITX2 antibody (142-192) (STJA0006624)

SKU:
STJA0006624
£48.00 - £252.00
Processing The item has been added

Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Pituitary homeobox 2 (142-192) is suitable for use in Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:1000-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PITX2
Gene ID: 5308
Uniprot ID: PITX2_HUMAN
Immunogen Region: 142-192
Specificity: This antibody detects endogenous levels of human PITX2
Immunogen: Synthesized peptide derived from human PITX2 AA range: 142-192
Function May play a role in myoblast differentiation. When unphosphorylated, associates with an ELAVL1-containing complex, which stabilizes cyclin mRNA and ensuring cell proliferation. Phosphorylation by AKT2 impairs this association, leading to CCND1 mRNA destabilization and progression towards differentiation. Isoform PTX2C: Involved in the establishment of left-right asymmetry in the developing embryo.
Protein Name Pituitary Homeobox 2
All1-Responsive Protein Arp1
Homeobox Protein Pitx2
Paired-Like Homeodomain Transcription Factor 2
Rieg Bicoid-Related Homeobox Transcription Factor
Solurshin
Database Links Reactome: R-HSA-8866906
Cellular Localisation Nucleus
Cytoplasm
Alternative Antibody Names Anti-Pituitary Homeobox 2 antibody
Anti-All1-Responsive Protein Arp1 antibody
Anti-Homeobox Protein Pitx2 antibody
Anti-Paired-Like Homeodomain Transcription Factor 2 antibody
Anti-Rieg Bicoid-Related Homeobox Transcription Factor antibody
Anti-Solurshin antibody
Anti-PITX2 antibody
Anti-ARP1 antibody
Anti-RGS antibody
Anti-RIEG antibody
Anti-RIEG1 antibody

Information sourced from Uniprot.org