• Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200 (4°C overnight). 2, Tris-EDTA, pH9.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 45min).

Anti-PINX1 antibody (121-170 aa) (STJ95097)

SKU:
STJ95097

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-PIN2/TERF1-interacting telomerase inhibitor 1 (121-170 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC 1:100-1:300
ELISA 1:20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PINX1
Gene ID: 54984
Uniprot ID: PINX1_HUMAN
Immunogen Region: 121-170 aa
Specificity: PinX1 Polyclonal Antibody detects endogenous levels of PinX1 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human PINX1 at the amino acid range 121-170
Post Translational Modifications Cleaved by enterovirus protease 3C to promote apoptosis.
Function Microtubule-binding protein essential for faithful chromosome segregation. Mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 binding to telomeres. Inhibits telomerase activity. May inhibit cell proliferation and act as tumor suppressor.
Protein Name Pin2/Terf1-Interacting Telomerase Inhibitor 1
Liver-Related Putative Tumor Suppressor
Pin2-Interacting Protein X1
Protein 67-11-3
Trf1-Interacting Protein 1
Cellular Localisation Nucleus
Nucleolus
Chromosome
Telomere
Centromere
Kinetochore
Localizes In Nucleoli
At Telomere Speckles And To The Outer Plate Of Kinetochores
Localization To The Kinetochore Is Mediated By Its Central Region And Depends On Ndc80 And Cenpe
Alternative Antibody Names Anti-Pin2/Terf1-Interacting Telomerase Inhibitor 1 antibody
Anti-Liver-Related Putative Tumor Suppressor antibody
Anti-Pin2-Interacting Protein X1 antibody
Anti-Protein 67-11-3 antibody
Anti-Trf1-Interacting Protein 1 antibody
Anti-PINX1 antibody
Anti-LPTL antibody
Anti-LPTS antibody

Information sourced from Uniprot.org

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