| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-PIMREG (1-247) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PIMREG |
| Gene ID: |
54478 |
| Uniprot ID: |
PIMRE_HUMAN |
| Immunogen Region: |
1-247 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-247 of human PIMREG (NP_001182157.1). |
| Immunogen Sequence: |
MASRWQNMGTSVRRRSLQHQ EQLEDSKELQPVVSHQETSV GALGSLCRQFQRRLPLRAVN LNLRAGPSWKRLETPEPGQQ GLQAAARSAKSALGAVSQRI |
| Tissue Specificity | Expressed in thymus (at protein level). Detected in spleen, colon, ovary and small intestines. |
| Post Translational Modifications | Ubiquitinated by the anaphase-promoting complex/cyclosome (APC/C) complex in the presence of FZR1, leading to its degradation by the proteasome during mitotic exit. However, degradation is not essential for normal mitotic progression within a single cell cycle. |
| Function | During mitosis, may play a role in the control of metaphase-to-anaphase transition. |
| Protein Name | Protein PimregCalm-Interactor Expressed In Thymus And SpleenPicalm-Interacting Mitotic RegulatorRegulator Of Chromosome Segregation Protein 1 |
| Cellular Localisation | NucleusNucleolusPartially Localizes To The Nucleolus |
| Alternative Antibody Names | Anti-Protein Pimreg antibodyAnti-Calm-Interactor Expressed In Thymus And Spleen antibodyAnti-Picalm-Interacting Mitotic Regulator antibodyAnti-Regulator Of Chromosome Segregation Protein 1 antibodyAnti-PIMREG antibodyAnti-CATS antibodyAnti-FAM64A antibodyAnti-RCS1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
