Western blot analysis of various lysates, using PIMREG antibody (STJ118662) at 1:700 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 30s.

Anti-PIMREG antibody (1-247) (STJ118662)

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STJ118662
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:1000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PIMREG
Gene ID: 54478
Uniprot ID: PIMRE_HUMAN
Immunogen Region: 1-247
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human PIMREG (NP_001182157.1).
Immunogen Sequence: MASRWQNMGTSVRRRSLQHQ EQLEDSKELQPVVSHQETSV GALGSLCRQFQRRLPLRAVN LNLRAGPSWKRLETPEPGQQ GLQAAARSAKSALGAVSQRI
Tissue Specificity Expressed in thymus (at protein level). Detected in spleen, colon, ovary and small intestines.
Post Translational Modifications Ubiquitinated by the anaphase-promoting complex/cyclosome (APC/C) complex in the presence of FZR1, leading to its degradation by the proteasome during mitotic exit. However, degradation is not essential for normal mitotic progression within a single cell cycle.
Function During mitosis, may play a role in the control of metaphase-to-anaphase transition.
Protein Name Protein Pimreg
Calm-Interactor Expressed In Thymus And Spleen
Picalm-Interacting Mitotic Regulator
Regulator Of Chromosome Segregation Protein 1
Cellular Localisation Nucleus
Nucleolus
Partially Localizes To The Nucleolus
Alternative Antibody Names Anti-Protein Pimreg antibody
Anti-Calm-Interactor Expressed In Thymus And Spleen antibody
Anti-Picalm-Interacting Mitotic Regulator antibody
Anti-Regulator Of Chromosome Segregation Protein 1 antibody
Anti-PIMREG antibody
Anti-CATS antibody
Anti-FAM64A antibody
Anti-RCS1 antibody

Information sourced from Uniprot.org

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