| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:1000IHC-P:1:50-1:100IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PIK3R3 |
| Gene ID: | 8503 |
| Uniprot ID: | P55G_HUMAN |
| Immunogen Region: | 300-388 |
| Immunogen Sequence: | PDLIQLRKIRDQHLVWLNHK GVRQKRLNVWLGIKNEDADE NYFINEEDENLPHYDEKTWF VEDINRVQAEDLLYGKPDGA FLIRESSKK |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 300-388 of human PIK3R3/p55PIK (NP_003620.3). |
| Tissue Specificity | Highest levels in brain and testis. Lower levels in adipose tissue, kidney, heart, lung and skeletal muscle. |
| Function | Binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During insulin stimulation, it also binds to IRS-1. |
| Protein Name | Phosphatidylinositol 3-Kinase Regulatory Subunit GammaPi3-Kinase Regulatory Subunit GammaPi3k Regulatory Subunit GammaPtdins-3-Kinase Regulatory Subunit GammaPhosphatidylinositol 3-Kinase 55 Kda Regulatory Subunit GammaPi3-Kinase Subunit P55-GammaPtdins-3-Kinase Regulatory Subunit P55-GammaP55pik |
| Database Links | Reactome: R-HSA-114604Reactome: R-HSA-1257604Reactome: R-HSA-1266695Reactome: R-HSA-1433557Reactome: R-HSA-1660499Reactome: R-HSA-2219530Reactome: R-HSA-389357Reactome: R-HSA-416476Reactome: R-HSA-512988Reactome: R-HSA-6811558Reactome: R-HSA-8853659Reactome: R-HSA-9009391Reactome: R-HSA-9013149Reactome: R-HSA-9013404Reactome: R-HSA-912526Reactome: R-HSA-912631Reactome: R-HSA-9670439Reactome: R-HSA-9927354 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Phosphatidylinositol 3-Kinase Regulatory Subunit Gamma antibodyAnti-Pi3-Kinase Regulatory Subunit Gamma antibodyAnti-Pi3k Regulatory Subunit Gamma antibodyAnti-Ptdins-3-Kinase Regulatory Subunit Gamma antibodyAnti-Phosphatidylinositol 3-Kinase 55 Kda Regulatory Subunit Gamma antibodyAnti-Pi3-Kinase Subunit P55-Gamma antibodyAnti-Ptdins-3-Kinase Regulatory Subunit P55-Gamma antibodyAnti-P55pik antibodyAnti-PIK3R3 antibody |
Information sourced from Uniprot.org
