Anti-PIK3CA-H1047Y Mutant antibody (STJA0033651)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from the internal region of PIK3CA which includes the mutation of H1047Y, human origin.
General Information
| Short Description | Mouse monoclonal anti-PIK3CA-H1047Y Mutant for use in WB, ICC, IF and ELISA in Vertebrates samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ICC/IF/ELISA |
| Host | Mouse |
| Reactivity | Vertebrates |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Purified from ascites |
| Dilution Range | WB-1:500-1:1000IHC-P-1:50-1:100ELISA-1:1000-1:5000IF-1:50-1:200 |
| Formulation | Liquid in PBS (without Mg2+Β and Ca2+) , pH 7.4, 150 mM NaCl, 50% glycerol |
| Storage Instruction | Store at-20Β°C. Avoid freeze/thaw cycles. |
Target Information
| Immunogen | A synthetic peptide from the internal region of PIK3CA which includes the mutation of H1047Y, human origin. |
Additional Info
| Background | Phosphatidyl 3-kinases (PI3K) are a family of lipid kinases involved in many cellular processes, including cell growth, proliferation, differentiation, motility, and survival. It is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. Mutants of PIK3CA has been found in the pathogenesis of several cancers, including colon cancer, gliomas, gastric cancer, breast cancer, endometrial cancer, and lung cancer. |
Information sourced from Uniprot.org