| Short Description : | Rabbit polyclonal PIGU (1-100) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PIGU |
| Gene ID: | 128869 |
| Uniprot ID: | PIGU_HUMAN |
| Immunogen Region: | 1-100 |
| Immunogen Sequence: | MAAPLVLVLVVAVTVRAALF RSSLAEFISERVEVVSPLSS WKRVVEGLSLLDLGVSPYSG AVFHETPLIIYLFHFLIDYA ELVFMITDALTAIALYFAIQ |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PIGU (NP_536724.1). |
| Function | Component of the glycosylphosphatidylinositol-anchor (GPI-anchor) transamidase (GPI-T) complex that catalyzes the formation of the linkage between a proprotein and a GPI-anchor and participates in GPI anchored protein biosynthesis. Binds the lipid portion of GPI-anchor. May act as an organizer in the transmembrane layer to recruit other subunits, and thus is essential for assembly of the complex. |
| Protein Name | Gpi-Anchor Transamidase Component PiguCell Division Cycle Protein 91-Like 1Protein Cdc91-Like 1Gpi Transamidase Component Pig-UPhosphatidylinositol Glycan Anchor Biosynthesis Class U Protein |
| Database Links | Reactome: R-HSA-162791 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Gpi-Anchor Transamidase Component Pigu antibodyAnti-Cell Division Cycle Protein 91-Like 1 antibodyAnti-Protein Cdc91-Like 1 antibodyAnti-Gpi Transamidase Component Pig-U antibodyAnti-Phosphatidylinositol Glycan Anchor Biosynthesis Class U Protein antibodyAnti-PIGU antibodyAnti-CDC91L1 antibodyAnti-PSEC0205 antibodyAnti-UNQ3055 antibodyAnti-PRO9875 antibody |
Information sourced from Uniprot.org
