Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rabbit polyclonal antibody anti-GPI-anchor transamidase (331-381 aa) is suitable for use in Western Blot research applications. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:1000-2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | PIGK |
Gene ID: | 10026 |
Uniprot ID: | GPI8_HUMAN |
Immunogen Region: | 331-381 aa |
Specificity: | This antibody detects endogenous levels of human GPI8 |
Immunogen: | Synthesized peptide derived from the human GPI8 at the amino acid range 331-381 |
Function | Component of the GPI transamidase complex, necessary for transfer of GPI to proteins. Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. |
Protein Name | Gpi-Anchor TransamidaseGpi TransamidaseGpi8 HomologHgpi8Phosphatidylinositol-Glycan Biosynthesis Class K ProteinPig-K |
Database Links | Reactome: R-HSA-162791 |
Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type I Membrane Protein |
Alternative Antibody Names | Anti-Gpi-Anchor Transamidase antibodyAnti-Gpi Transamidase antibodyAnti-Gpi8 Homolog antibodyAnti-Hgpi8 antibodyAnti-Phosphatidylinositol-Glycan Biosynthesis Class K Protein antibodyAnti-Pig-K antibodyAnti-PIGK antibodyAnti-GPI8 antibody |
Information sourced from Uniprot.org