Anti-PI3R6 antibody (590-640) {Biotin} (STJ506051)

SKU:
STJ506051-100

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Host: Rabbit
Applications: ELISA/IP/WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-PI3R6 (590-640) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Biotin
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.5-1.5 µg/µl
Dilution Range: WB: 1:500
ELISA: 1:50, 000
IP: 1:200
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: PIK3R6
Gene ID: 146850
Uniprot ID: PI3R6_HUMAN
Immunogen Region: 590-640
Immunogen: Synthetic peptide taken within amino acid region 590-640 on human PhosphoInositide 3-kinase regulatory subunit 6.
Function Regulatory subunit of the PI3K gamma complex. Acts as an adapter to drive activation of PIK3CG by beta-gamma G protein dimers. The PIK3CG:PIK3R6 heterodimer is much less sensitive to beta-gamma G protein dimers than PIK3CG:PIK3R5 and its membrane recruitment and beta-gamma G protein dimer-dependent activation requires HRAS bound to PIK3CG. Recruits of the PI3K gamma complex to a PDE3B:RAPGEF3 signaling complex involved in angiogenesis.signaling seems to involve RRAS.
Protein Name Phosphoinositide 3-Kinase Regulatory Subunit 6
Phosphoinositide 3-Kinase Gamma Adapter Protein Of 87 Kda
P84 Pi3k Adapter Protein
P84 Pikap
P87 Pi3k Adapter Protein
P87pikap
Database Links Reactome: R-HSA-114604
Reactome: R-HSA-1660499
Reactome: R-HSA-392451
Cellular Localisation Cytoplasm
Cell Membrane
Peripheral Membrane Protein
Translocated To The Plasma Membrane In A Ras-Dependent Manner
Alternative Antibody Names Anti-Phosphoinositide 3-Kinase Regulatory Subunit 6 antibody
Anti-Phosphoinositide 3-Kinase Gamma Adapter Protein Of 87 Kda antibody
Anti-P84 Pi3k Adapter Protein antibody
Anti-P84 Pikap antibody
Anti-P87 Pi3k Adapter Protein antibody
Anti-P87pikap antibody
Anti-PIK3R6 antibody
Anti-C17orf38 antibody

Information sourced from Uniprot.org

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