| Host: |
Rabbit |
| Applications: |
IHC |
| Reactivity: |
Human/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-PI3 (23-117) is suitable for use in Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
IHC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PI3 |
| Gene ID: |
5266 |
| Uniprot ID: |
ELAF_HUMAN |
| Immunogen Region: |
23-117 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 23-117 of human PI3 (NP_002629.1). |
| Immunogen Sequence: |
AVTGVPVKGQDTVKGRVPFN GQDPVKGQVSVKGQDKVKAQ EPVKGPVSTKPGSCPIILIR CAMLNPPNRCLKDTDCPGIK KCCEGSCGMACFVPQ |
| Function | Neutrophil and pancreatic elastase-specific inhibitor of skin. It may prevent elastase-mediated tissue proteolysis. Has been shown to inhibit the alpha-4-beta-2/CHRNA2-CHRNB2 nicotinic acetylcholine receptor and to produce a weak inhibition on Kv11.1/KCNH2/ERG1 and on the transient receptor potential cation channel subfamily V member 1 (TRPV1). |
| Protein Name | ElafinElastase-Specific InhibitorEsiPeptidase Inhibitor 3Pi-3Protease Inhibitor Wap3Skin-Derived AntileukoproteinaseSkalpWap Four-Disulfide Core Domain Protein 14 |
| Database Links | Reactome: R-HSA-6803157Reactome: R-HSA-6809371 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Elafin antibodyAnti-Elastase-Specific Inhibitor antibodyAnti-Esi antibodyAnti-Peptidase Inhibitor 3 antibodyAnti-Pi-3 antibodyAnti-Protease Inhibitor Wap3 antibodyAnti-Skin-Derived Antileukoproteinase antibodyAnti-Skalp antibodyAnti-Wap Four-Disulfide Core Domain Protein 14 antibodyAnti-PI3 antibodyAnti-WAP3 antibodyAnti-WFDC14 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
