• Western blot analysis of lysates from wild type (WT) and PHOX2B knockdown (KD) SH-SY5Y cells using [KD Validated]PHOX2B Rabbit polyclonal antibody (STJ11104636) at 1:1000 dilution. Secondary antibody:HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25  Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection:ECL Basic Kit. Exposuretime: 10s.
  • Western blot analysis of lysates from Neuro-2a cells using [KD Validated]PHOX2B Rabbit polyclonal antibody (STJ11104636) at 1:1000 dilution. Secondary antibody:HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25  Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection:ECL Basic Kit. Exposuretime:10s.

Anti-PHOX2B antibody (260-314) (STJ11104636)

SKU:
STJ11104636

£129.50 - £639.50
Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Paired Mesoderm Homeobox Protein 2b (260-314) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PHOX2B
Gene ID: 8929
Uniprot ID: PHX2B_HUMAN
Immunogen Region: 260-314
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 260-314 of human PHOX2B (NP_003915.2).
Immunogen Sequence: AGGLAAAGGPGQGWAPGPGP ITSIPDSLGGPFASVLSSLQ RPNGAKAALVKSSMF
Tissue Specificity Expressed in neuroblastoma, brain and adrenal gland.
Function Involved in the development of several major noradrenergic neuron populations, including the locus coeruleus. Transcription factor which could determine a neurotransmitter phenotype in vertebrates. Enhances second-messenger-mediated activation of the dopamine beta-hydrolase and c-fos promoters, and of several enhancers including cAMP-response element and serum-response element.
Protein Name Paired Mesoderm Homeobox Protein 2b
Neuroblastoma Phox
Nbphox
Phox2b Homeodomain Protein
Paired-Like Homeobox 2b
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Paired Mesoderm Homeobox Protein 2b antibody
Anti-Neuroblastoma Phox antibody
Anti-Nbphox antibody
Anti-Phox2b Homeodomain Protein antibody
Anti-Paired-Like Homeobox 2b antibody
Anti-PHOX2B antibody
Anti-PMX2B antibody

Information sourced from Uniprot.org

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