Anti-Phospholipase C beta 1 antibody [R03-6E6] (STJA0034722)

SKU:
STJA0034722
£133.50 - £281.50
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: Rabbit
Applications: WB
Reactivity: Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal anti-Phospholipase C beta 1 for use in WB in Rat samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : R03-6E6
Conjugation: Unconjugated
Isotype: IgG
Formulation: 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Purification: Affinity Purified
Concentration: 0.3 mg/mL
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol: Plcb1
Gene ID: 18795
Uniprot ID: PLCB1_MOUSE
Immunogen: Recombinant protein of mouse Phospholipase C beta 1
Post Translational Modifications Palmitoylated. Palmitoylation at Cys-17 by ZDHHC21 regulates the signaling activity of PLCB1 and the function of the endothelial barrier (Probable). Palmitoylation by ZDHHC21 is stimulated by inflammation.
Function Catalyzes the hydrolysis of 1-phosphatidylinositol 4,5-bisphosphate into diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) and mediates intracellular signaling downstream of G protein-coupled receptors. Regulates the function of the endothelial barrier.
Protein Name 1-Phosphatidylinositol 4 -5-Bisphosphate Phosphodiesterase Beta-1
Plc-154
Phosphoinositide Phospholipase C-Beta-1
Phospholipase C-Beta-1
Plc-Beta-1
Database Links Reactome: R-MMU-112043
Reactome: -MMU-1855204
Reactome: -MMU-399997
Reactome: -MMU-4086398
Reactome: -MMU-416476
Reactome: -MMU-418217
Reactome: -MMU-434316
Reactome: -MMU-500657
Cellular Localisation Nucleus Membrane
Cytoplasm
Colocalizes With The Adrenergic Receptors
Adren1a And Adren1b
At The Nuclear Membrane Of Cardiac Myocytes
Alternative Antibody Names Anti-1-Phosphatidylinositol 4 -5-Bisphosphate Phosphodiesterase Beta-1 antibody
Anti-Plc-154 antibody
Anti-Phosphoinositide Phospholipase C-Beta-1 antibody
Anti-Phospholipase C-Beta-1 antibody
Anti-Plc-Beta-1 antibody
Anti-Plcb1 antibody
Anti-Plcb antibody

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJA0034371 Anti-Glutathione Peroxidase 4 antibody [R03-6E6] (STJA0034371) Rabbit Monoclonal Human/Rat WB/IHC-F/IHC-P/ICC/IF
STJA0037286 Anti-Phospholipase C beta 3 antibody [R08-9L1] (STJA0037286) Rabbit Monoclonal Human WB/IHC-P
STJA0036208 Anti-IL-1 beta antibody [R03-6K4] (STJA0036208) Rabbit Monoclonal Human WB
STJA0033448 Anti-TGF beta Receptor I antibody [4H5-6E6-7H2] (STJA0033448) Mouse Monoclonal Human IHC-P
STJA0035229 Anti-Hsp90 beta antibody [R03-8F1] (STJA0035229) Rabbit Monoclonal Human/Mouse/Rat WB/IHC-P

Related Products

!