Anti-Phospho-VAV2-Tyr142 antibody (108-157 aa) (STJ91109)

SKU:
STJ91109
£49.00 - £261.00
Processing The item has been added

Short Description :Rabbit polyclonal anti-Phospho-Guanine nucleotide exchange factor VAV2-Tyr142 (108-157 aa) for use in WB, IHC, IF and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/IHC/IF/ELISA
Host:Rabbit
Reactivity:Human/Mouse
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:10000
Formulation:Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:VAV2
Gene ID:7410
Uniprot ID:VAV2_HUMAN
Immunogen:The antiserum was produced against synthesized peptide derived from the human VAV2 around the phosphorylation site of Tyr142 at the amino acid range 108-157
Immunogen Region:108-157 aa
Specificity:Phospho-Vav2 (Y142) Polyclonal Antibody detects endogenous levels of Vav2 protein only when phosphorylated at Y142.
Post Translational Modifications Phosphorylated on tyrosine residues in response to FGR activation.
Function Guanine nucleotide exchange factor for the Rho family of Ras-related GTPases. Plays an important role in angiogenesis. Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly.
Protein Name Guanine Nucleotide Exchange Factor Vav2
Vav-2
Database Links Reactome: R-HSA-114604
Reactome: R-HSA-193648
Reactome: R-HSA-2029482
Reactome: R-HSA-2424491
Reactome: R-HSA-2871796
Reactome: R-HSA-2871809
Reactome: R-HSA-3928665
Reactome: R-HSA-416482
Reactome: R-HSA-4420097
Reactome: R-HSA-445144
Reactome: R-HSA-5218920
Reactome: R-HSA-8980692
Reactome: R-HSA-9013026
Reactome: R-HSA-9013106
Reactome: R-HSA-9013148
Reactome: R-HSA-9013149
Reactome: R-HSA-9013404
Reactome: R-HSA-9013408
Reactome: R-HSA-9013423
Reactome: R-HSA-9664422
Reactome: R-HSA-9748787
Cellular Localisation
Alternative Antibody Names Anti-Guanine Nucleotide Exchange Factor Vav2 antibody
Anti-Vav-2 antibody
Anti-VAV2 antibody

Information sourced from Uniprot.org