• Immunohistochemistry analysis of paraffin-embedded human brain, using VAV2 (Phospho-Tyr142) Antibody. The picture on the right is blocked with the phospho peptide.
  • Western blot analysis of lysates from HeLa cells and K562 cells treated with TNF 20ng/ml 30', using VAV2 (Phospho-Tyr142) Antibody. The lane on the right is blocked with the phospho peptide.
  • Immunofluorescence analysis of NIH/3T3 cells, using VAV2 (Phospho-Tyr142) Antibody. The picture on the right is blocked with the phospho peptide.

Anti-Phospho-VAV2-Tyr142 antibody (108-157 aa) (STJ91109)

SKU:
STJ91109

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Phospho-Guanine nucleotide exchange factor VAV2-Tyr142 (108-157 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:10000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: VAV2
Gene ID: 7410
Uniprot ID: VAV2_HUMAN
Immunogen Region: 108-157 aa
Specificity: Phospho-Vav2 (Y142) Polyclonal Antibody detects endogenous levels of Vav2 protein only when phosphorylated at Y142.
Immunogen: The antiserum was produced against synthesized peptide derived from the human VAV2 around the phosphorylation site of Tyr142 at the amino acid range 108-157
Post Translational Modifications Phosphorylated on tyrosine residues in response to FGR activation.
Function Guanine nucleotide exchange factor for the Rho family of Ras-related GTPases. Plays an important role in angiogenesis. Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly.
Protein Name Guanine Nucleotide Exchange Factor Vav2
Vav-2
Database Links Reactome: R-HSA-114604
Reactome: R-HSA-193648
Reactome: R-HSA-2029482
Reactome: R-HSA-2424491
Reactome: R-HSA-2871796
Reactome: R-HSA-2871809
Reactome: R-HSA-3928665
Reactome: R-HSA-416482
Reactome: R-HSA-4420097
Reactome: R-HSA-445144
Reactome: R-HSA-5218920
Reactome: R-HSA-8980692
Reactome: R-HSA-9013026
Reactome: R-HSA-9013106
Reactome: R-HSA-9013148
Reactome: R-HSA-9013149
Reactome: R-HSA-9013404
Reactome: R-HSA-9013408
Reactome: R-HSA-9013423
Reactome: R-HSA-9664422
Reactome: R-HSA-9748787
Alternative Antibody Names Anti-Guanine Nucleotide Exchange Factor Vav2 antibody
Anti-Vav-2 antibody
Anti-VAV2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance