• Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200 (4°C overnight). 2, Tris-EDTA, pH9.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 45min).

Anti-Phospho-VAV1-Tyr160 antibody (131-180 aa) (STJ91129)

SKU:
STJ91129

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Phospho-Proto-oncogene vav-Tyr160 (131-180 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC 1:100-1:300
ELISA 1:5000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: VAV1
Gene ID: 7409
Uniprot ID: VAV_HUMAN
Immunogen Region: 131-180 aa
Specificity: Phospho-Vav (Y160) Polyclonal Antibody detects endogenous levels of Vav protein only when phosphorylated at Y160.
Immunogen: The antiserum was produced against synthesized peptide derived from the human VAV1 around the phosphorylation site of Tyr160 at the amino acid range 131-180
Post Translational Modifications Phosphorylated on tyrosine residues by HCK in response to IFNG and bacterial lipopolysaccharide (LPS). Phosphorylated by FYN.
Function Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation.
Protein Name Proto-Oncogene Vav
Database Links Reactome: R-HSA-114604
Reactome: R-HSA-1257604
Reactome: R-HSA-1433557
Reactome: R-HSA-193648
Reactome: R-HSA-2029482
Reactome: R-HSA-2219530
Reactome: R-HSA-2871796
Reactome: R-HSA-2871809
Reactome: R-HSA-389359
Reactome: R-HSA-416482
Reactome: R-HSA-4420097
Reactome: R-HSA-512988
Reactome: R-HSA-5218920
Reactome: R-HSA-6811558
Reactome: R-HSA-8980692
Reactome: R-HSA-9013149
Reactome: R-HSA-9013404
Reactome: R-HSA-9013408
Reactome: R-HSA-9027284
Reactome: R-HSA-912631
Reactome: R-HSA-9664422
Reactome: R-HSA-9679191
Reactome: R-HSA-9748787
Reactome: R-HSA-983695
Alternative Antibody Names Anti-Proto-Oncogene Vav antibody
Anti-VAV1 antibody
Anti-VAV antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance