| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S3MR |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | VANGL2 |
| Gene ID: | 57216 |
| Uniprot ID: | VANG2_HUMAN |
| Specificity: | A phospho specific peptide corresponding to residues surrounding T78/S79/S82 of human VANGL2 |
| Immunogen Sequence: | TSEHS |
| Function | Involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. Plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. Required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process. Required for cell surface localization of FZD3 and FZD6 in the inner ear. |
| Protein Name | Vang-Like Protein 2 Loop-Tail Protein 1 Homolog Strabismus 1 Van Gogh-Like Protein 2 |
| Database Links | Reactome: R-HSA-4086400 Reactome: R-HSA-4608870 Reactome: R-HSA-9696264 Reactome: R-HSA-9696270 Reactome: R-HSA-9696273 |
| Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Vang-Like Protein 2 antibody Anti-Loop-Tail Protein 1 Homolog antibody Anti-Strabismus 1 antibody Anti-Van Gogh-Like Protein 2 antibody Anti-VANGL2 antibody Anti-KIAA1215 antibody Anti-STB1 antibody |
Information sourced from Uniprot.org