Anti-Phospho-VANGL2-T78/S79 antibody [S2MR] (STJ11103742)

SKU:
STJ11103742

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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-Phospho-VANGL2-T78/S79 is suitable for use in Western Blot research applications.
Clonality: Monoclonal
Clone ID: S2MR
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: VANGL2
Gene ID: 57216
Uniprot ID: VANG2_HUMAN
Immunogen: A phospho specific peptide corresponding to residues surrounding T78/S79 of human VANGL2
Immunogen Sequence: Email for sequence
Function Involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. Plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. Required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process. Required for cell surface localization of FZD3 and FZD6 in the inner ear.
Protein Name Vang-Like Protein 2
Loop-Tail Protein 1 Homolog
Strabismus 1
Van Gogh-Like Protein 2
Database Links Reactome: R-HSA-4086400
Reactome: R-HSA-4608870
Reactome: R-HSA-9696264
Reactome: R-HSA-9696270
Reactome: R-HSA-9696273
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Vang-Like Protein 2 antibody
Anti-Loop-Tail Protein 1 Homolog antibody
Anti-Strabismus 1 antibody
Anti-Van Gogh-Like Protein 2 antibody
Anti-VANGL2 antibody
Anti-KIAA1215 antibody
Anti-STB1 antibody

Information sourced from Uniprot.org

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