• Western blot of recombinant tryptophan hydroxylase incubated in the absence (-) and presence (+) of cAMP-dependent protein kinase showing specific immunolabeling of the ~55 kDa tryptophan hydroxylase protein phosphorylated at Ser58.

Anti-Phospho-TPH1-Ser58 antibody (STJA0003813)

SKU:
STJA0003813-100

£442.50
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Host: Rabbit
Applications: WB
Reactivity: Mouse/Rabbit/Bovine/Chicken/Human/Non-Human Primates/Rat/Xenopus/Zebrafish
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Phospho-Tryptophan Hydroxylase-Ser58 is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 100 µl in 10 mM HEPES (pH 7.5) , 150 mM NaCl, 100 µg per ml BSA and 50% Glycerol.
Purification: This antibody was antigen affinity purified from pooled serum.
Dilution Range: WB 1:1000
IHC
ICC
IP
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: Tph1
Gene ID: 24848
Uniprot ID: TPH1_RAT
Immunogen: Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser58 conjugated to KLH.
Post Translational Modifications Ubiquitinated, leading to its degradation by the proteasome. Ubiquitinated is triggered by phosphorylation. Phosphorylated.triggering degradation by the proteasome.
Function Oxidizes L-tryptophan to 5-hydroxy-l-tryptophan in the rate-determining step of serotonin biosynthesis.
Protein Name Tryptophan 5-Hydroxylase 1
Tryptophan 5-Monooxygenase 1
Database Links Reactome: R-RNO-209931
Alternative Antibody Names Anti-Tryptophan 5-Hydroxylase 1 antibody
Anti-Tryptophan 5-Monooxygenase 1 antibody
Anti-Tph1 antibody
Anti-Tph antibody

Information sourced from Uniprot.org

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