Anti-Phospho-TNK1-Tyr277 antibody (STJ196454)

SKU:
STJ196454

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Phospho-Non-receptor tyrosine-protein kinase TNK1-Tyr277 is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:1000-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TNK1
Gene ID: 8711
Uniprot ID: TNK1_HUMAN
Specificity: This antibody detects endogenous levels of Human TNK1 (phospho-Tyr277)
Immunogen: Synthesized phosho peptide around human TNK1 (Tyr277)
Post Translational Modifications Autophosphorylated on tyrosine residues.
Function Involved in negative regulation of cell growth. Has tumor suppressor properties. Plays a negative regulatory role in the Ras-MAPK pathway. May function in signaling pathways utilized broadly during fetal development and more selectively in adult tissues and in cells of the lymphohematopoietic system. Could specifically be involved in phospholipid signal transduction.
Protein Name Non-Receptor Tyrosine-Protein Kinase Tnk1
Cd38 Negative Kinase 1
Cellular Localisation Cytoplasm
Membrane
Peripheral Membrane Protein
Alternative Antibody Names Anti-Non-Receptor Tyrosine-Protein Kinase Tnk1 antibody
Anti-Cd38 Negative Kinase 1 antibody
Anti-TNK1 antibody

Information sourced from Uniprot.org

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