• Immunohistochemistry analysis of paraffin-embedded human brain, using Synapsin1 (Phospho-Ser605) Antibody. The picture on the right is blocked with the phospho peptide.
  • Immunofluorescence analysis of COS7 cells, using Synapsin1 (Phospho-Ser605) Antibody. The picture on the right is blocked with the phospho peptide.

Anti-Phospho-SYN1-Ser605 antibody (576-625 aa) (STJ91309)

SKU:
STJ91309

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Phospho-Synapsin-1-Ser605 (576-625 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SYN1
Gene ID: 6853
Uniprot ID: SYN1_HUMAN
Immunogen Region: 576-625 aa
Specificity: Phospho-Synapsin I (S605) Polyclonal Antibody detects endogenous levels of Synapsin I protein only when phosphorylated at S605.
Immunogen: The antiserum was produced against synthesized peptide derived from the human Synapsin1 around the phosphorylation site of Ser605 at the amino acid range 576-625
Function Neuronal phosphoprotein that coats synaptic vesicles, and binds to the cytoskeleton. Acts as a regulator of synaptic vesicles trafficking, involved in the control of neurotransmitter release at the pre-synaptic terminal. Also involved in the regulation of axon outgrowth and synaptogenesis. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level.
Protein Name Synapsin-1
Brain Protein 4.1
Synapsin I
Database Links Reactome: R-HSA-181429
Reactome: R-HSA-212676
Reactome: R-HSA-9662360
Cellular Localisation Synapse
Golgi Apparatus
Presynapse
Cytoplasmic Vesicle
Secretory Vesicle
Synaptic Vesicle
Dissociates From Synaptic Vesicles And Redistributes Into The Axon During Action Potential Firing
In A Step That Precedes Fusion Of Vesicles With The Plasma Membrane
Reclusters To Presynapses After The Cessation Of Synaptic Activity
Alternative Antibody Names Anti-Synapsin-1 antibody
Anti-Brain Protein 4.1 antibody
Anti-Synapsin I antibody
Anti-SYN1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance