Anti-Phospho-STAT5A-Tyr-694 antibody [M148] (STJA0005608)

SKU:
STJA0005608-100

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Host: Mouse
Applications: WB/ICC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Phospho-Stat5-Tyr-694 is suitable for use in Western Blot and Immunocytochemistry research applications.
Clonality: Monoclonal
Clone ID: M148
Conjugation: Unconjugated
Isotype: IgG1
Formulation: PBS + 1 mg/ml BSA, 0.05% NaN3 and 50% glycerol
Purification: Antigen Affinity Purified
Dilution Range: WB 1:1000
IHC
ICC 1:100
IP
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: STAT5A
Gene ID: 6776
Uniprot ID: STA5A_HUMAN
Specificity: The antibody detects a 92 kDa* band corresponding to Stat5A on SDS-PAGE immunoblots of human A431 cells treated with EGF, but does not detect this band in control cells.
Immunogen: Clone (M148) was generated from a synthetic peptide (coupled to KLH) corresponding to amino acid residues around tyrosine 694 of human Stat5A. This peptide sequence is identical to tyrosine 699 in human Stat5B, and has high homology to the conserved
Function Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Mediates cellular responses to ERBB4. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the GAS element and activates PRL-induced transcription. Regulates the expression of milk proteins during lactation.
Protein Name Signal Transducer And Activator Of Transcription 5a
Database Links Reactome: R-HSA-1170546
Reactome: R-HSA-1251985
Reactome: R-HSA-1266695
Reactome: R-HSA-1433557
Reactome: R-HSA-1839117
Reactome: R-HSA-186763
Reactome: R-HSA-2586552
Reactome: R-HSA-512988
Reactome: R-HSA-8854691
Reactome: R-HSA-8983432
Reactome: R-HSA-8985947
Reactome: R-HSA-9020558
Reactome: R-HSA-9020958
Reactome: R-HSA-9027283
Reactome: R-HSA-9645135
Reactome: R-HSA-9670439
Reactome: R-HSA-9674555
Reactome: R-HSA-9702518
Reactome: R-HSA-9703465
Reactome: R-HSA-9705462
Reactome: R-HSA-9725371
Reactome: R-HSA-982772
Cellular Localisation Cytoplasm
Nucleus
Translocated Into The Nucleus In Response To Phosphorylation
Alternative Antibody Names Anti-Signal Transducer And Activator Of Transcription 5a antibody
Anti-STAT5A antibody
Anti-STAT5 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance