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Anti-Phospho-Stat5-Ser726/731 antibody (697-746 aa) (STJ90773)

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using STAT5B (Phospho-Ser731) Antibody. The picture on the right is blocked with the phospho peptide.
Western blot analysis of lysates from RAW264.7 cells treated with EGF 200ng/ml 30', using STAT5B (Phospho-Ser731) Antibody. The lane on the right is blocked with the phospho peptide.
Western blot analysis of various cells using Phospho-Stat5 (S726/731) Polyclonal Antibody diluted at 1：500

Anti-Phospho-Stat5-Ser726/731 antibody (697-746 aa) (STJ90773)

SKU:

STJ90773

£46.00 - £226.00

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General Information
Product Properties
Target Information
Additional Info
Warranty Information

Host:	Rabbit
Applications:	WB/IHC/IF/ELISA
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Phospho-Signal transducer and activator of transcription 5A and Signal transducer and activator of transcription 5B-Ser726/731 (697-746 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-1:2000 IHC 1:100-1:300 ELISA 1:40000 IF 1:50-200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	STAT5B STAT5A
Gene ID:	6777 6776
Uniprot ID:	STA5B_HUMAN STA5A_HUMAN
Immunogen Region:	697-746 aa
Specificity:	Phospho-Stat5 (S726/731) Polyclonal Antibody detects endogenous levels of Stat5 protein only when phosphorylated at S726/731.
Immunogen:	The antiserum was produced against synthesized peptide derived from the human STAT5B around the phosphorylation site of Ser731 at the amino acid range 697-746

Function	Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Mediates cellular responses to ERBB4. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the GAS element and activates PRL-induced transcription. Regulates the expression of milk proteins during lactation.
Protein Name	Signal Transducer And Activator Of Transcription 5a
Database Links	Reactome: R-HSA-1170546 Reactome: R-HSA-1251985 Reactome: R-HSA-1266695 Reactome: R-HSA-1433557 Reactome: R-HSA-1839117 Reactome: R-HSA-186763 Reactome: R-HSA-2586552 Reactome: R-HSA-512988 Reactome: R-HSA-8854691 Reactome: R-HSA-8983432 Reactome: R-HSA-8985947 Reactome: R-HSA-9020558 Reactome: R-HSA-9020958 Reactome: R-HSA-9027283 Reactome: R-HSA-9645135 Reactome: R-HSA-9670439 Reactome: R-HSA-982772
Cellular Localisation	Cytoplasm Nucleus Translocated Into The Nucleus In Response To Phosphorylation
Alternative Antibody Names	Anti-Signal Transducer And Activator Of Transcription 5a antibody Anti-STAT5A antibody Anti-STAT5 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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